General Cell Lines and Cell Cultures
Eurofins Discoverx Ready-to-Assay M1 Acetylcholine (Muscarinic) Receptor Frozen Cells, 2 Vials of Cells. (HTS044RTA)
The Ready-to-Assay M1 Acetylcholine (Muscarinic) Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. acetylcholine) based activation of CHRM1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Gardnerella vaginalis
Gardnerella vaginalis strain AmMS 117 is a whole-genome sequenced clinical isolate that can be used as a quality control strain for MicroScan products.
ATCC Organoid Growth Kit 1B
ATCC Growth Kits are packages of recombinant proteins, small molecules and other supplements designed to make the preparation of complex media formulations for select organoid culture models easy and reliable. Kit components are supplied as powders to maximize stability and in convenient, pre-portioned, ready-to-reconstitute format that does not require aliquoting or storage once prepared.
ATCC JeKo-1; Mantle Cell Lymphoma; Human (Homo sapiens)
The JeKo-1 mantle cell lymphoma (MCL) cell line was isolated from the peripheral blood mononuclear cells of a 78-year-old female with a large cell variant of MCL showing leukemic conversion. The JeKo-1 cells are highly tumorigenic in SCID mice and has applications for immunology research.
ATCC Blastocystis hominis; NandII
Blastocystis hominis strain Nand II is a parasitic protozoan that was isolated in 1979 from a human in Bethesda, Maryland. This product has applications in enteric disease research.
ATCC Synthetic Middle East; respiratory syndrome; coronavirus RNA
Quantitative synthetic RNA for Middle East respiratory syndrome coronavirus can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load and for other molecular biology applications. This preparation includes fragments from the ORF1ab, ORF5, upper envelope (upE), ORF8b, nucleocapsid (N) protein gene, and 3' UTR regions.
Amsbio LLC Human Endometrial cancer and normal adjacent tissue FFPE block
Human Endometrial cancer and normal adjacent tissue FFPE block
iQ Biosciences Purified BALB/c Mouse CD3 Pan T Cells, 5M cells/vial
High-quality, high-viability (typically > 70%) mouse CD3 Pan T cells purified from spleen of BALB/c strain of mice. Highly enriched (> 90%) post-selection purity achieved via magnetic isolation. All orders come with an iQ Certificate of Analysis.
Eurofins Discoverx PathHunter U2OS GHSR1a β-Arrestin-1 Cell Line, 2 vials. (93-0242C3)
The PathHunter GHSR1a (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR1a GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1a and EA-tagged β-Arrestin-1. Activation of GHSR1a stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
New England Biolabs, Inc. NEB® 10-beta Competent E. coli (High Efficiency) – 1 96-well plate (20µL/well)
NEB 10-beta Competent E. coli is a derivative of the popular DH10B. It is T1 phage resistant and endonuclease I (endA1) deficient for high- quality plasmid preparations.
- High efficiency strain ideal for cloning large plasmids and BACs
- Also available in chemically-competent format (single-use and 200 µl vials)
- No dry ice surcharge on competent cell shipments
- Outgrowth medium included
- Free of animal products
Biolegend PE anti-mouse CD24 Recombinant
PE anti-mouse CD24 Recombinant [QA20A91]; Isotype: Mouse IgG1, κ; Reactivity: Mouse; Apps: FC; Size: 100 ug
Eurofins Discoverx PathHunter U2OS EphA4 Functional Assay, 2 vials. (93-0877C3)
The PathHunter U2OS EphA4 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphA4 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphA4 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
